The Effect of Thioacetamide on Urea Cycle Enzymes of Rat Liver

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Induction of urea cycle enzymes of rat liver by glucagon.

All five urea cycle enzymes of rat liver increased in activity 48 h after subcutaneous administration of crystalline zinc glucagon to male rats and remained elevated after 7 days of continuous glucagon infusion. The maximum ratios of enzyme activities over those of controls were 2.0 for carbamyl phosphate synthetase, 1.3 for ornithine transcarbamylase, 2.7 for argininosuccinate synthetase, 3.2 ...

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Effect of Thioacetamide on Rat Liver Regeneration

The effect of thioacetamide on dividing cells of regenerating rat liver has been studied. Rats were given daily subcutaneous injections of thioacetamide as a 1 per cent solution at a dosage of 5 mg./100 gm. body weight for 7 to 10 days, subjected to partial hepatectomy, and sacrificed 28 to 31 hours later. Thioacetamide treatment results in striking increases in the nuclear ribonucleoproteins o...

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ژورنال

عنوان ژورنال: Clinical Chemistry and Laboratory Medicine

سال: 1979

ISSN: 1434-6621,1437-4331

DOI: 10.1515/cclm.1979.17.3.129